Anti-DOPA Decarboxylase/DDC抗体(ab233132)
Key features and details
- Rabbit polyclonal to DOPA Decarboxylase/DDC
- Suitable for: WB, IHC-P
- Reacts with: Cow, Human
- Isotype: IgG
概述
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产品名称
Anti-DOPA Decarboxylase/DDC抗体
参阅全部 DOPA Decarboxylase/DDC 一抗 -
描述
兔多克隆抗体to DOPA Decarboxylase/DDC -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Cow, Human -
免疫原
Recombinant fragment (His-T7-tag) corresponding to Human DOPA Decarboxylase/DDC aa 200-450. Two N-terminal tags.Expressed in E.coli.
Database link: P20711-1 -
阳性对照
- WB: Recombinant human DOPA Decarboxylase/DDC protein; Cow kidney lysate. IHC-P: Human lung tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 44.12% PBS, 55.77% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab233132于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 54 kDa.
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IHC-P |
Use a concentration of 5 - 20 µg/ml.
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说明 |
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WB
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 54 kDa. |
IHC-P
Use a concentration of 5 - 20 µg/ml. |
靶标
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功能
Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. -
通路
Catecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 2/2. -
疾病相关
Defects in DDC are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) [MIM:608643]. AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive. -
序列相似性
Belongs to the group II decarboxylase family. - Information by UniProt
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数据库链接
- Entrez Gene: 280762 Cow
- Entrez Gene: 1644 Human
- Omim: 107930 Human
- SwissProt: P27718 Cow
- SwissProt: P20711 Human
- Unigene: 359698 Human
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别名
- AADC antibody
- Aromatic L Amino Acid Decarboxylase antibody
- Aromatic-L-amino-acid decarboxylase antibody
see all
图片
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Anti-DOPA Decarboxylase/DDC antibody (ab233132) at 2 µg/ml + Recombinant human DOPA Decarboxylase/DDC protein
Predicted band size: 54 kDa -
Anti-DOPA Decarboxylase/DDC antibody (ab233132) at 2 µg/ml + Cow kidney tissue lysate
Predicted band size: 54 kDa -
Anti-DOPA Decarboxylase/DDC antibody (ab233132) at 2 µg/ml + Cow kidney tissue lysate
Secondary
HRP-Linked Guinea pig anti-Rabbit at 1/1000 dilution
Predicted band size: 54 kDa -
Formalin-fixed, paraffin-embedded human lung tissue stained for DOPA Decarboxylase/DDC using ab233132 at 20 μg/ml in immunohistochemical analysis. DAB staining.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab233132 尚未被引用在任何文献中。