Anti-DOCK7抗体[3540C1a] (ab84866)

概述

  • 产品名称
    Anti-DOCK7抗体[3540C1a]
    参阅全部 DOCK7 一抗
  • 描述
    小鼠单克隆抗体[3540C1a] to DOCK7
  • 经测试应用
    适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Recombinant fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment with a tag, corresponding to internal sequence amino acids 1003-1112 of Human DOCK7

  • 阳性对照
    • Immunising recombinant Human DOCK7 protein.

性能

应用

Our Abpromise guarantee covers the use of ab84866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 243 kDa.
Dot blot Use at an assay dependent dilution.

靶标

  • 相关性
    DOCK7 functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. It does not have a GEF activity for CDC42. It is required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization.
  • 细胞定位
    Cell projection, axon. Note=Enriched in the developing axons of hippocampal neurons.
  • 数据库链接
  • 别名
    • 3110056M06Rik antibody
    • dedicator of cytokinesis 7 antibody
    • Dedicator of cytokinesis protein 7 antibody
    • Gm430 antibody
    • KIAA1771 antibody
    • MGC189434 antibody
    • mKIAA1771 antibody
    • RP23 329P19.2 antibody
    • ZIR2 antibody
    see all

Anti-DOCK7 antibody [3540C1a] 图像

实验方案

Anti-DOCK7 antibody [3540C1a] (ab84866)参考文献

ab84866 has not yet been referenced specifically in any publications.

Product Wall

Application
Western blot
Sample
Mouse Cell lysate - other (HEK293T and platelets of human and mouse origin)
Gel Running Conditions
Reduced Denaturing (4-12%)
Loading amount
30 µg
Specification
HEK293T and platelets of human and mouse origin
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 21°C
Username

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提交于 Jun 14 2017

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