Anti-DNER抗体(ab57949)

概述

  • 产品名称Anti-DNER抗体
    参阅全部 DNER 一抗
  • 描述
    小鼠单克隆抗体to DNER
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 368-477 of Human DNER

  • 阳性对照
    • PC-12 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab57949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 90-100 kDa (predicted molecular weight: 78.4 kDa). Larger band size is due to glycosylation.

靶标

  • 功能Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
  • 组织特异性Expressed in brain, spinal cord and adrenal gland.
  • 序列相似性Contains 10 EGF-like domains.
    Contains 1 follistatin-like domain.
  • 细胞定位Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
  • Information by UniProt
  • 数据库链接
  • 别名
    • bet antibody
    • Brain EGF repeat-containing transmembrane protein antibody
    • Bret antibody
    • Delta and Notch-like epidermal growth factor-related receptor antibody
    • Delta notch like EGF repeat containing transmembrane antibody
    • Delta/notch like EGF repeat containing antibody
    • Delta/notch-like EGF-related receptor antibody
    • Dner antibody
    • DNER_HUMAN antibody
    • PRO299 antibody
    • Transmembrane protein Bet antibody
    • UNQ26 antibody
    see all

Anti-DNER antibody 图像



  • Predicted band size : 78.4 kDa

    Western Blot analysis of DNER antibody (ab57949).

Anti-DNER antibody (ab57949)参考文献

ab57949 has not yet been referenced specifically in any publications.

Product Wall

Thank you for the inquiry. The calculated predicted molecular weight of DNER is indeed 78.4KDa but the protein is glycosylated, hence when testing on PC12 cell lysate a band at around 100kDa was detected. This band size has been reported in the lit...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"