• 产品名称Anti-Dnd1抗体
    参阅全部 Dnd1 一抗
  • 描述
    小鼠单克隆抗体to Dnd1
  • 经测试应用适用于: WB, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein tagged with GST (Human)



Our Abpromise guarantee covers the use of ab57770 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml.
Flow Cyt Use 0.5µg for 106 cells. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.


  • 功能RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration.
  • 序列相似性Contains 2 RRM (RNA recognition motif) domains.
  • 细胞定位Nucleus. Cytoplasm. Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Dead end homolog 1 (zebrafish) antibody
    • dead end homolog 1 antibody
    • Dead end protein antibody
    • Dead end protein homolog 1 antibody
    • Dead end, zebrafish, homolog, 1 antibody
    • DND microRNA-mediated repression inhibitor 1 antibody
    • dnd1 antibody
    • DND1_HUMAN antibody
    • MGC34750 antibody
    • RBMS4 antibody
    • RNA binding motif single stranded interacting protein 4 antibody
    • RNA-binding motif antibody
    • single-stranded-interacting protein 4 antibody
    • Ter antibody
    see all

Anti-Dnd1 antibody 图像

  • Dnd1 antibody (ab57770) at 1ug/lane + HeLa cell lysate at 25ug/lane.
  • Overlay histogram showing HeLa cells stained with ab57770 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab57770, 0.5µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive signal in HeLa cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

  • Anti-Dnd1 antibody (ab57770) + PC12
  • Anti-Dnd1 antibody (ab57770) + Raw 264.7
  • Anti-Dnd1 antibody (ab57770) + NIH/3T3

Anti-Dnd1 antibody (ab57770)参考文献

ab57770 has not yet been referenced specifically in any publications.

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