概述

描述

  • 性质
    Synthetic

技术指标

Our Abpromise guarantee covers the use of ab8373 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.1% BSA

常规信息

  • 别名
    • Acid DNase
    • Deoxyribonuclease 2
    • Deoxyribonuclease 2 alpha
    • Deoxyribonuclease II
    • Deoxyribonuclease II alpha
    • Deoxyribonuclease II lysosomal
    • Deoxyribonuclease-2-alpha
    • Deoxyribonuclease2
    • DeoxyribonucleaseII
    • DNASE 2
    • DNASE 2A
    • DNase II alpha
    • DNase II lysosomal
    • DNASE2
    • DNASE2A
    • DNaseII
    • DNL
    • DNL 2
    • DNL2
    • DNS2A_HUMAN
    • Lysosomal DNase II
    • R31240 2
    • R31240_2
    see all
  • 功能
    Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
  • 序列相似性
    Belongs to the DNase II family.
  • 翻译后修饰
    Glycosylated. Mutations that eliminate N-glycosylation sites reduce activity, but enzymatic deglycosylation has no effect.
  • 细胞定位
    Lysosome.
  • Information by UniProt

文献

ab8373 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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