RabMAb

Anti-DNAJC3抗体[EP597Y] (ab52899)

概述

  • 产品名称Anti-DNAJC3抗体[EP597Y]
    参阅全部 DNAJC3 一抗
  • 描述
    兔单克隆抗体[EP597Y] to DNAJC3
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC/IF or IHC-P
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues near the N terminus of human DNAJC3.

  • 阳性对照
    • HeLa cell lysate.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab52899 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 53 kDa (predicted molecular weight: 58 kDa).
  • 应用说明Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
  • 靶标

    • 功能Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
    • 组织特异性Widely expressed with high level in the pancreas and testis. Also expressed in cell lines with different levels.
    • 序列相似性Contains 1 J domain.
      Contains 9 TPR repeats.
    • 结构域The J domain mediates interaction with HSPA8.
    • 细胞定位Endoplasmic reticulum.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DnaJ (Hsp40) homolog subfamily C member 3 antibody
      • DnaJ homolog subfamily C member 3 antibody
      • DNAJC3 antibody
      • DNJC3_HUMAN antibody
      • double-stranded RNA-activated protein kinase inhibitor antibody
      • Endoplasmic reticulum DnaJ protein 6 antibody
      • ERdj6 antibody
      • HP58 antibody
      • Interferon induced, double stranded RNA activated protein kinase inhibitor antibody
      • Interferon-induced antibody
      • P58 antibody
      • p58 ipk antibody
      • P58IPK antibody
      • PRKRI antibody
      • Protein kinase inhibitor of 58 kDa antibody
      • Protein kinase inhibitor p58 antibody
      • Protein kinase interferon inducible double stranded RNA dependent inhibitor antibody
      see all

    Anti-DNAJC3 antibody [EP597Y] 图像

    • Anti-DNAJC3 antibody [EP597Y] (ab52899) at 1/1000 dilution + HeLa cell lysate at 10 µg

      Secondary
      goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 58 kDa
      Observed band size : 53 kDa (why is the actual band size different from the predicted?)

    Anti-DNAJC3 antibody [EP597Y] (ab52899)参考文献

    ab52899 has not yet been referenced specifically in any publications.

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