概述

  • 产品名称Anti-DNAJC3抗体
    参阅全部 DNAJC3 一抗
  • 描述
    小鼠单克隆抗体to DNAJC3
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-235 of Human DNAJC3

性能

应用

Our Abpromise guarantee covers the use of ab57737 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ICC/IF
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IF/ICC: Use at a concentration of 10 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
    • 组织特异性Widely expressed with high level in the pancreas and testis. Also expressed in cell lines with different levels.
    • 序列相似性Contains 1 J domain.
      Contains 9 TPR repeats.
    • 结构域The J domain mediates interaction with HSPA8.
    • 细胞定位Endoplasmic reticulum.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DnaJ (Hsp40) homolog subfamily C member 3 antibody
      • DnaJ homolog subfamily C member 3 antibody
      • DNAJC3 antibody
      • DNJC3_HUMAN antibody
      • double-stranded RNA-activated protein kinase inhibitor antibody
      • Endoplasmic reticulum DnaJ protein 6 antibody
      • ERdj6 antibody
      • HP58 antibody
      • Interferon induced, double stranded RNA activated protein kinase inhibitor antibody
      • Interferon-induced antibody
      • P58 antibody
      • p58 ipk antibody
      • P58IPK antibody
      • PRKRI antibody
      • Protein kinase inhibitor of 58 kDa antibody
      • Protein kinase inhibitor p58 antibody
      • Protein kinase interferon inducible double stranded RNA dependent inhibitor antibody
      see all

    Anti-DNAJC3 antibody 图像

    • DNAJC3 antibody (ab57737) used in immunofluorescence at 10ug/ml on HeLa cells.
    • Western blot against tagged recombinant protein immunogen using ab57737 DNAJC3 antibody at 1ug/ml. Predicted band size of immunogen is 52 kDa

    Anti-DNAJC3 antibody (ab57737)参考文献

    ab57737 has not yet been referenced specifically in any publications.

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