概述

  • 产品名称Anti-DNAJC19抗体
    参阅全部 DNAJC19 一抗
  • 描述
    小鼠多克隆抗体to DNAJC19
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow, Orangutan
  • 免疫原

    DNAJC19 full-length human protein (NP_660304.1, 1 a.a. ~ 116 a.a).

性能

应用

Our Abpromise guarantee covers the use of ab70092 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 12 kDa.

靶标

  • 功能Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity.
  • 组织特异性Ubiquitously expressed.
  • 疾病相关Defects in DNAJC19 are the cause of 3-methylglutaconic aciduria type 5 (MGA5) [MIM:610198]; also known as dilated cardiomyopathy with ataxia (DCMA). MGA5 is an autosomal recessive disorder characterized by early-onset dilated cardiomyopathy, growth failure, cerebellar ataxia causing significant motor delays, testicular dysgenesis, growth failure, and significant increases in urine organic acids, particularly 3-methylglutaconic acid and 3-methylglutaric acid.
  • 序列相似性Belongs to the TIM14 family.
    Contains 1 J domain.
  • 细胞定位Mitochondrion inner membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DnaJ (Hsp40) homolog, subfamily C, member 19 antibody
    • DnaJ homolog subfamily C member 19 antibody
    • DNAJC19 antibody
    • homolog of yeast TIM14 antibody
    • Mitochondrial import inner membrane translocase subunit TIM14 antibody
    • PAM18 antibody
    • TIM 14 antibody
    • TIM14 antibody
    • TIM14_HUMAN antibody
    • TIMM 14 antibody
    • TIMM14 antibody
    • translocase of the inner mitochondrial membrane 14 antibody
    • Translocase of the inner mitochondrial membrane 14, yeast homolog of antibody
    see all

Anti-DNAJC19 antibody 图像

  • All lanes : Anti-DNAJC19 antibody (ab70092) at 1/500 dilution

    Lane 1 : DNAJC19 transfected lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 12 kDa

Anti-DNAJC19 antibody (ab70092)参考文献

ab70092 has not yet been referenced specifically in any publications.

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