概述

  • 产品名称Anti-DNAJB11抗体
    参阅全部 DNAJB11 一抗
  • 描述
    兔多克隆抗体to DNAJB11
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 62-92 of Human DNAJB11 (NP_057390.1).

  • 阳性对照
    • NCI-H460 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab112959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.

靶标

  • 功能Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.
  • 组织特异性Widely expressed.
  • 序列相似性Contains 1 J domain.
  • 翻译后修饰Contains high-mannose Endo H-sensitive carbohydrates.
    Cys-169, Cys-171, Cys-193 and Cys-196 form intramolecular disulfide bonds. The preferential partner for each Cys is not known.
    Thr-188 was reported (PubMed:17525332) to be phosphorylated upon DNA damage by ATM or ATR; however as this position has been shown to be in the ER lumen, the in vivo relevance is not proven.
  • 细胞定位Endoplasmic reticulum lumen. Associated with the ER membrane in a C-terminally epitope-tagged construct.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ABBP-2 antibody
    • ABBP2 antibody
    • APOBEC1 binding protein 2 antibody
    • APOBEC1-binding protein 2 antibody
    • DJ9 antibody
    • DJB11_HUMAN antibody
    • DnaJ (Hsp40) homolog subfamily B member 11 antibody
    • DnaJ homolog subfamily B member 11 antibody
    • DnaJ protein homolog 9 antibody
    • DNAJB11 antibody
    • EDJ antibody
    • ER associated DNAJ antibody
    • ER associated dnaJ protein 3 antibody
    • ER associated Hsp40 co chaperone antibody
    • ER-associated DNAJ antibody
    • ER-associated dnaJ protein 3 antibody
    • ER-associated Hsp40 co-chaperone antibody
    • ERdj3 antibody
    • ERJ3 antibody
    • ERj3p antibody
    • hDj-9 antibody
    • hDj9 antibody
    • HEDJ antibody
    • Human DnaJ protein 9 antibody
    • PWP1 interacting protein 4 antibody
    • PWP1-interacting protein 4 antibody
    see all

Anti-DNAJB11 antibody 图像

  • Anti-DNAJB11 antibody (ab112959) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

    Predicted band size : 41 kDa

Anti-DNAJB11 antibody (ab112959)参考文献

ab112959 has not yet been referenced specifically in any publications.

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