The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明IHC-P: 1/100 - 1/500.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with Frozen Sections.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
组织特异性Expressed in a number of tissues. Abundant in testis.
序列相似性Belongs to the DNA polymerase type-X family. Contains 1 BRCT domain.
翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.