Anti-DNA Polymerase lambda抗体(ab82919)

概述

  • 产品名称Anti-DNA Polymerase lambda抗体
    参阅全部 DNA Polymerase lambda 一抗
  • 描述
    兔多克隆抗体to DNA Polymerase lambda
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide, corresponding to a region within internal sequence amino acids 525 - 574 (SLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERD W) of Human DNA Polymerase lambda, (NP_037406)

  • 阳性对照
    • Fetal brain lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab82919 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 63 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/12500.

靶标

  • 功能Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  • 组织特异性Expressed in a number of tissues. Abundant in testis.
  • 序列相似性Belongs to the DNA polymerase type-X family.
    Contains 1 BRCT domain.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BETA N antibody
    • BETAN antibody
    • DNA directed DNA polymerase lambda antibody
    • DNA polymerase beta 2 antibody
    • DNA polymerase beta-2 antibody
    • DNA polymerase kappa antibody
    • DNA polymerase kappa DNA polymerase beta N antibody
    • DNA polymerase lambda antibody
    • DNA polymerase lamda2 antibody
    • DPOLL_HUMAN antibody
    • EC 2.7.7.7,EC 4.2.99. antibody
    • FLJ46002 antibody
    • OTTHUMP00000020321 antibody
    • OTTHUMP00000020323 antibody
    • OTTHUMP00000059179 antibody
    • Pol beta2 antibody
    • POL KAPPA antibody
    • Pol Lambda antibody
    • POLKAPPA antibody
    • POLL antibody
    • Polymerase DNA directed lambda antibody
    see all

Anti-DNA Polymerase lambda antibody 图像

  • Anti-DNA Polymerase lambda antibody (ab82919) at 1 µg/ml + fetal brain lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 63 kDa
    Observed band size : 63 kDa

Anti-DNA Polymerase lambda antibody (ab82919)参考文献

ab82919 has not yet been referenced specifically in any publications.

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