Anti-DNA Polymerase epsilon抗体(ab84532)

概述

  • 产品名称Anti-DNA Polymerase epsilon抗体
    参阅全部 DNA Polymerase epsilon 一抗
  • 描述
    兔多克隆抗体to DNA Polymerase epsilon
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Guinea pig, Cow, Chimpanzee, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan, Bat
  • 免疫原

    A region between residue 97 and 147 of human DNA polymerase epsilon (NP_059139.2)

  • 阳性对照
    • Human Anaplastic Thyroid Carcinoma, Bladder Cell Carcinoma, Breast Carcinoma, Colon Carcinoma, Metastatic Lymph Node, Ovarian Carcinoma, Prostate Carcinoma, Skin Basal Cell Carcinoma, Small Cell Lung Cancer, Stomach Adenocarcinoma or Testicular Seminoma tissue. Mouse Teratoma tissue.
  • 常规说明Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG. Shelf Life: 1 year from date of receipt

性能

应用

Our Abpromise guarantee covers the use of ab84532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. In some cases, the antibody may be diluted further than indicated.

    Likely to work with frozen sections

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
    • 组织特异性Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Arsenic transactivated protein antibody
      • Arsenic-transactivated protein antibody
      • ASTP antibody
      • CHARAC 17 antibody
      • CHARAC17 antibody
      • CHRAC 17 antibody
      • CHRAC-17 antibody
      • CHRAC17 antibody
      • Chromatin Accessibility Complex 17 antibody
      • Chromatin accessibility complex 17 kDa protein antibody
      • DNA Polymerase Epsilon p17 Subunit antibody
      • DNA polymerase epsilon subunit 3 antibody
      • DNA polymerase epsilon subunit p17 antibody
      • DNA polymerase II subunit 3 antibody
      • DPOE3_HUMAN antibody
      • Histone fold protein CHRAC17 antibody
      • HuCHRAC 17 antibody
      • HuCHRAC17 antibody
      • p17 antibody
      • p17 subunit antibody
      • POL E3 antibody
      • POLE 3 antibody
      • POLE3 antibody
      • Polymerase (DNA directed) epsilon 3 antibody
      • YBL 1 antibody
      • YBL1 antibody
      see all

    Anti-DNA Polymerase epsilon antibody 图像

    • ab84532, at a 1:100 dilution, staining human DNA polymerase epsilon in breast carcinoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue. Detection: DAB staining using an Immunohistochemistry Accessory Kit
    • ab84532, at a 1:500 dilution, staining human DNA polyermase epsilon in colon carcinoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue. Detection: DAB staining using an Immunohistochemistry Accessory Kit
    • ab84532, at a 1:100 dilution, staining mouse DNA polymerase epsilon in teratoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue. Detection: DAB staining using an Immunohistochemistry Accessory Kit

    Anti-DNA Polymerase epsilon antibody (ab84532)参考文献

    ab84532 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"