Anti-DNA Polymerase beta (di methyl R83)抗体(ab93673)

概述

  • 产品名称Anti-DNA Polymerase beta (di methyl R83)抗体
    参阅全部 DNA Polymerase beta 一抗
  • 描述
    兔多克隆抗体to DNA Polymerase beta (di methyl R83)
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to the N terminal residues of Human DNA Polymerase beta.

性能

应用

Our Abpromise guarantee covers the use of ab93673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA 1/2000 - 1/5000.

靶标

  • 功能Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  • 序列相似性Belongs to the DNA polymerase type-X family.
  • 结构域Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.
  • 翻译后修饰Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DNA directed DNA polymerase beta antibody
    • DNA pol beta antibody
    • DNA polymerase beta antibody
    • DNA polymerase beta subunit antibody
    • DPOLB_HUMAN antibody
    • MGC125976 antibody
    • Pol B antibody
    • Pol beta antibody
    • POLB antibody
    • Polymerase (DNA directed) beta antibody
    see all

Anti-DNA Polymerase beta (di methyl R83) antibody (ab93673)参考文献

ab93673 has not yet been referenced specifically in any publications.

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