Anti-DNA Polymerase beta抗体[SPM177], prediluted (ab53923)

概述

  • 产品名称Anti-DNA Polymerase beta抗体[SPM177], prediluted
    参阅全部 DNA Polymerase beta 一抗
  • 描述
    小鼠单克隆抗体[SPM177] to DNA Polymerase beta, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    DNA polymerase beta protein.

  • 阳性对照
    • Hela cells and human testis.

性能

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应用

Our Abpromise guarantee covers the use of ab53923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready to use for 60 min at room temperature .

    Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    • 序列相似性Belongs to the DNA polymerase type-X family.
    • 结构域Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.
    • 翻译后修饰Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DNA directed DNA polymerase beta antibody
      • DNA pol beta antibody
      • DNA polymerase beta antibody
      • DNA polymerase beta subunit antibody
      • DPOLB_HUMAN antibody
      • MGC125976 antibody
      • Pol B antibody
      • Pol beta antibody
      • POLB antibody
      • Polymerase (DNA directed) beta antibody
      see all

    Anti-DNA Polymerase beta antibody [SPM177], prediluted 图像

    • ab53923 (prediluted) staining DNA Polymerase Beta in formalin fixed, paraffin embedded human testis tissue by Immunohistochemistry.

    Anti-DNA Polymerase beta antibody [SPM177], prediluted (ab53923)参考文献

    ab53923 has not yet been referenced specifically in any publications.

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