Anti-DNA PKcs (phospho S2056)抗体- ChIP Grade (ab18192)

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ab18192 被引用在 38 文献中.

  • DeLoughery Z  et al. DNA double-strand breaks by Cr(VI) are targeted to euchromatin and cause ATR-dependent phosphorylation of histone H2AX and its ubiquitination. Toxicol Sci 143:54-63 (2015). PubMed: 25288669
  • Wilson JE  et al. Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nat Med N/A:N/A (2015). PubMed: 26107252
  • Burdine LJ  et al. Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway. PLoS One 10:e0127943 (2015). WB ; Human . PubMed: 26065416
  • Al-Mashhadi S  et al. Oxidative Glial Cell Damage Associated with White Matter Lesions in the Aging Human Brain. Brain Pathol N/A:N/A (2014). WB ; Human . PubMed: 25311358
  • Zhou Y  et al. Quantitation of DNA double-strand break resection intermediates in human cells. Nucleic Acids Res 42:e19 (2014). ChIP ; Human . PubMed: 24362840
  • Yu H  et al. Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair. Proc Natl Acad Sci U S A 111:285-90 (2014). PubMed: 24347639
  • Gad H  et al. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature 508:215-21 (2014). PubMed: 24695224
  • Peng M  et al. Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses. EMBO J N/A:N/A (2014). WB, ICC/IF ; Human . PubMed: 24966277
  • Neal JA  et al. Unraveling the Complexities of DNA-Dependent Protein Kinase Autophosphorylation. Mol Cell Biol 34:2162-75 (2014). WB . PubMed: 24687855
  • Montano R  et al. Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo. BMC Cancer 13:604 (2013). WB ; Human . PubMed: 24359526
  • Valerie NC  et al. Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells. Biochem Pharmacol 85:888-97 (2013). PubMed: 23287412
  • Calkins AS  et al. DNA damage-induced inhibition of rRNA synthesis by DNA-PK and PARP-1. Nucleic Acids Res 41:7378-86 (2013). PubMed: 23775790
  • Shawi M  et al. Telomerase contributes to fludarabine resistance in primary human leukemic lymphocytes. PLoS One 8:e70428 (2013). Flow Cyt ; Human . PubMed: 23922990
  • Chatterjee P  et al. Defective chromatin recruitment and retention of NHEJ core components in human tumor cells expressing a Cyclin E fragment. Nucleic Acids Res N/A:N/A (2013). PubMed: 24021630
  • Tu WZ  et al. ?H2AX foci formation in the absence of DNA damage: Mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway. FEBS Lett 587:3437-43 (2013). PubMed: 24021642
  • Yajima H  et al. The complexity of DNA double strand breaks is a critical factor enhancing end-resection. DNA Repair (Amst) 12:936-46 (2013). PubMed: 24041488
  • Boisvert RA  et al. Coordinate Nuclear Targeting of the FANCD2 and FANCI Proteins via a FANCD2 Nuclear Localization Signal. PLoS One 8:e81387 (2013). ICC/IF . PubMed: 24278431
  • Zhou Y & Paull TT DNA-dependent protein kinase regulates DNA end resection in concert with Mre11-Rad50-Nbs1 (MRN) and ataxia telangiectasia-mutated (ATM). J Biol Chem 288:37112-25 (2013). Human . PubMed: 24220101
  • Meek K  et al. N-terminal constraint activates the catalytic subunit of the DNA-dependent protein kinase in the absence of DNA or Ku. Nucleic Acids Res 40:2964-73 (2012). WB . PubMed: 22167471
  • Furusawa Y  et al. DNA double-strand breaks induced by cavitational mechanical effects of ultrasound in cancer cell lines. PLoS One 7:e29012 (2012). ICC/IF ; Human . PubMed: 22235259
  • Kang MA  et al. Deregulation of DNA damage response pathway by intercellular contact. J Biol Chem 287:16246-55 (2012). WB . PubMed: 22431734
  • Bouquet F  et al. A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia. J Cell Sci 124:1943-51 (2011). PubMed: 21576354
  • Sakasai R  et al. Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin. DNA Repair (Amst) 9:76-82 (2010). PubMed: 19959400
  • Velkova A  et al. Identification of filamin A as a BRCA1-interacting protein required for efficient DNA repair. Cell Cycle 9: (2010). WB ; Human . PubMed: 20305393
  • Shang ZF  et al. Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage. Cancer Res 70:3657-66 (2010). WB ; Human . PubMed: 20406977
  • Sakasai R  et al. Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison. J Biol Chem 285:15201-8 (2010). WB ; Human . PubMed: 20304914
  • White JS  et al. Transient ATM kinase inhibition disrupts DNA damage-induced sister chromatid exchange. Sci Signal 3:ra44 (2010). PubMed: 20516478
  • Brugat T  et al. Telomere dysfunction-induced foci arise with the onset of telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells. Blood 116:239-49 (2010). ICC/IF ; Human . PubMed: 20424183
  • Zhu H  et al. Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining. PLoS One 5: (2010). WB ; Human . PubMed: 20700465
  • Massip L  et al. Deciphering the chromatin landscape induced around DNA double strand breaks. Cell Cycle 9:2963-72 (2010). ICC/IF, ChIP ; Human . PubMed: 20714222
  • Bensimon A  et al. ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage. Sci Signal 3:rs3 (2010). WB ; Human . PubMed: 21139141
  • Marston E  et al. Stratification of pediatric ALL by in vitro cellular responses to DNA double-strand breaks provides insight into the molecular mechanisms underlying clinical response. Blood 113:117-26 (2009). WB ; Human . PubMed: 18941120
  • Solier S  et al. Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. Mol Cell Biol 29:68-82 (2009). WB ; Human . PubMed: 18955500
  • Tsai CY  et al. Targeting DNA repair in chronic lymphocytic leukemia cells with a novel acyclic nucleotide analogue, GS-9219. Clin Cancer Res 15:3760-9 (2009). WB ; Human . PubMed: 19435836
  • Tomimatsu N  et al. Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells. EMBO Rep 10:629-35 (2009). PubMed: 19444312
  • Mordes DA  et al. TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes Dev 22:1478-89 (2008). WB . PubMed: 18519640
  • Willmore E  et al. DNA-Dependent Protein Kinase Is a Therapeutic Target and an Indicator of Poor Prognosis in B-Cell Chronic Lymphocytic Leukemia. Clin Cancer Res 14:3984-3992 (2008). WB, Flow Cyt ; Human . PubMed: 18559621
  • Douglas P  et al. The DNA-dependent protein kinase catalytic subunit is phosphorylated in vivo on threonine 3950, a highly conserved amino acid in the protein kinase domain. Mol Cell Biol 27:1581-91 (2007). WB ; Human . PubMed: 17158925

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