Anti-DMAP1抗体- Carboxyterminal end (ab71789)

概述

  • 产品名称Anti-DMAP1抗体- Carboxyterminal end
    参阅全部 DMAP1 一抗
  • 描述
    兔多克隆抗体to DMAP1 - Carboxyterminal end
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the C-terminal region of human DMAP1.

  • 阳性对照
    • Human hepatocarcinoma tissue and HL60 cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab71789 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 53 kDa (predicted molecular weight: 53 kDa).
ELISA 1/1000.
IHC-P 1/50 - 1/100.

靶标

  • 相关性DMAP1 is involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • DKFZp686L09142 antibody
    • DMAP 1 antibody
    • DNA methyltransferase 1 associated protein 1 antibody
    • DNMAP 1 antibody
    • DNMAP1 antibody
    • DNMT1 associated protein 1 antibody
    • DNMTAP 1 antibody
    • DNMTAP1 antibody
    • EAF 2 antibody
    • EAF2 antibody
    • FLJ11543 antibody
    • KIAA1425 antibody
    • MAT 1 mediated transcriptional repressor antibody
    • MGC55593 antibody
    • SWC 4 antibody
    • SWC4 antibody
    • zgc:55593 antibody
    see all

Anti-DMAP1 antibody - Carboxyterminal end 图像

  • Anti-DMAP1 antibody - Carboxyterminal end (ab71789) at 1/100 dilution + HL60 cell lysate at 12.5 µg

    Predicted band size : 53 kDa
    Observed band size : 53 kDa
  • Formalin-fixed, paraffin-embedded human hepatocarcinoma tissue reacted with ab71789 at a 1:50 dilution, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

Anti-DMAP1 antibody - Carboxyterminal end (ab71789)参考文献

ab71789 has not yet been referenced specifically in any publications.

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