概述

  • 产品名称Anti-DLL3抗体
    参阅全部 DLL3 一抗
  • 描述
    兔多克隆抗体to DLL3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 550 to the C-terminus of Human DLL3.

    (Peptide available as ab88189.)

  • 阳性对照
    • This antibody gave a positive signal in Human Liver Tissue Lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab63707 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 65 kDa (predicted molecular weight: 65 kDa).

靶标

  • 功能Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
  • 疾病相关Spondylocostal dysostosis 1
  • 序列相似性Contains 1 DSL domain.
    Contains 6 EGF-like domains.
  • 结构域The DSL domain is required for binding to the Notch receptor.
  • 翻译后修饰Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Delta Drosophila like 3 antibody
    • Delta like 3 Drosophila antibody
    • Delta like 3 homolog Drosophila antibody
    • Delta like 3 protein antibody
    • Delta like protein 3 precursor antibody
    • Delta-like protein 3 antibody
    • Delta3 antibody
    • Dll3 antibody
    • DLL3_HUMAN antibody
    • Drosophila Delta homolog 3 antibody
    • SCDO1 antibody
    • SCOD1 antibody
    • Spondylocostal dysostosis autosomal recessive antibody
    see all

Anti-DLL3 antibody 图像

  • Anti-DLL3 antibody (ab63707) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 65 kDa
    Observed band size : 65 kDa

Anti-DLL3 antibody (ab63707)参考文献

ab63707 has not yet been referenced specifically in any publications.

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