概述

  • 产品名称
  • 描述
    兔多克隆抗体to DLL3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 550 to the C-terminus of Human DLL3.

    (Peptide available as ab88189.)

  • 阳性对照
    • This antibody gave a positive signal in Human Liver Tissue Lysate.

性能

应用

Our Abpromise guarantee covers the use of ab63707 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 65 kDa (predicted molecular weight: 65 kDa).

靶标

  • 功能
    Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
  • 疾病相关
    Spondylocostal dysostosis 1
  • 序列相似性
    Contains 1 DSL domain.
    Contains 6 EGF-like domains.
  • 结构域
    The DSL domain is required for binding to the Notch receptor.
  • 翻译后修饰
    Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Delta Drosophila like 3 antibody
    • Delta like 3 Drosophila antibody
    • Delta like 3 homolog Drosophila antibody
    • Delta like 3 protein antibody
    • Delta like protein 3 precursor antibody
    • Delta-like protein 3 antibody
    • Delta3 antibody
    • Dll3 antibody
    • DLL3_HUMAN antibody
    • Drosophila Delta homolog 3 antibody
    • SCDO1 antibody
    • SCOD1 antibody
    • Spondylocostal dysostosis autosomal recessive antibody
    see all

图片

  • Anti-DLL3 antibody (ab63707) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 65 kDa
    Observed band size : 65 kDa

实验方案

文献

ab63707 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab63707.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册