概述

  • 产品名称Anti-DLL1抗体[4F8]
    参阅全部 DLL1 一抗
  • 描述
    小鼠单克隆抗体[4F8] to DLL1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: QVWSSGVFEL KLQEFVNKKG LLGNRNCCRG GAGPPPCACR TFFRVCLKHY QASVSPEPPC TYGSAVTPVL GVDSFSLPDG GGADSAFSNP IR, corresponding to amino acids 18-110 of Human Delta like 1

应用

Our Abpromise guarantee covers the use of ab57308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
    • 组织特异性Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.
    • 序列相似性Contains 1 DSL domain.
      Contains 8 EGF-like domains.
    • 翻译后修饰Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Delta (Drosophila) like 1 antibody
      • Delta antibody
      • Delta like 1 (Drosophila) antibody
      • Delta like 1 antibody
      • Delta like 1 protein antibody
      • Delta like protein 1 antibody
      • Delta like protein 1 precursor antibody
      • Delta, Drosophila, homolog of 1 antibody
      • Delta-like protein 1 antibody
      • Delta1 antibody
      • DL1 antibody
      • DLL 1 antibody
      • DLL1 antibody
      • DLL1_HUMAN antibody
      • Drosophila Delta homolog 1 antibody
      • H-Delta-1 antibody
      • OTTHUMP00000017690 antibody
      see all

    Anti-DLL1 antibody [4F8] 图像

    • Western blot against tagged recombinant protein immunogen using ab57308 Delta like 1 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    Anti-DLL1 antibody [4F8] (ab57308)参考文献

    ab57308 has not yet been referenced specifically in any publications.

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