概述

  • 产品名称Anti-DLG5抗体
    参阅全部 DLG5 一抗
  • 描述
    小鼠单克隆抗体to DLG5
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1708-1810 of Human DLG5

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration. PubMed: 21294127
WB Use a concentration of 1 - 5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

靶标

  • 功能May play a role at the plasma membrane in the maintenance of the structure of epithelial cells and in the transmission of extracellular signals to the membrane and cytoskeleton.
  • 组织特异性Highly expressed in the placenta and prostate. Expressed at a lower level in the thyroid, spinal cord, trachea, adrenal gland, skeletal muscle, pancreas, heart, brain, liver and kidney. A short splice product shows more limited expression, being absent from at least the brain.
  • 序列相似性Belongs to the MAGUK family.
    Contains 1 CARD domain.
    Contains 1 guanylate kinase-like domain.
    Contains 4 PDZ (DHR) domains.
    Contains 1 SH3 domain.
  • 细胞定位Cell junction. Cell membrane. Localized at sites of cell-cell contact.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Discs large homolog 5 (Drosophila) antibody
    • Discs large homolog 5 antibody
    • Discs large protein LP DLG antibody
    • Discs large protein P dlg antibody
    • Discs large protein P-dlg antibody
    • Disks large homolog 5 antibody
    • DLG 5 antibody
    • DLG5 antibody
    • DLG5_HUMAN antibody
    • KIAA0583 antibody
    • Large type of P DLG antibody
    • LP DLG antibody
    • P DLG5 antibody
    • PDLG antibody
    • Placenta and prostate DLG antibody
    see all

Anti-DLG5 antibody 图像

  • Western blot against tagged recombinant protein immunogen using ab56492 DLG5 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

Anti-DLG5 antibody (ab56492)参考文献

This product has been referenced in:
  • Saben J  et al. A comprehensive analysis of the human placenta transcriptome. Placenta 35:125-31 (2014). Human . Read more (PubMed: 24333048) »
  • Ruiz C  et al. Amplification and overexpression of vinculin are associated with increased tumour cell proliferation and progression in advanced prostate cancer. J Pathol 223:543-52 (2011). IHC-P ; Human . Read more (PubMed: 21294127) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab56492.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"