概述

  • 产品名称Anti-DLEC1抗体
    参阅全部 DLEC1 一抗
  • 描述
    兔多克隆抗体to DLEC1
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence, corresponding to internal sequence amino acids 186-298 of Human DLEC1.

  • 阳性对照
    • Human cerebral cortex tissue; U 2 OS cells.

性能

应用

Our Abpromise guarantee covers the use of ab121589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

靶标

  • 功能May act as a tumor suppressor by inhibiting cell proliferation.
  • 组织特异性Expressed in all tissues examined. Expression is highest in prostate and testis.
  • 疾病相关DLEC1 silencing due to promoter methylation and aberrant transcription are implicated in the development of different cancers, including esophageal (ESCR), renal and lung cancers (LNCR).
    Lung cancer
    Esophageal cancer
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Deleted in lung and esophageal cancer 1 antibody
    • Deleted in lung and esophageal cancer 1 transcript varient 2 antibody
    • Deleted in lung and esophageal cancer protein 1 antibody
    • Deleted in lung cancer protein 1 antibody
    • DLC 1 antibody
    • Dlc-1 antibody
    • DLC1 antibody
    • Dlec1 antibody
    • DLEC1_HUMAN antibody
    • F56 antibody
    see all

Anti-DLEC1 antibody 图像

  • ab121589, at a 1/225 dilution, staining DLEC1 in neuronal cells of paraffin-embedded Human cerebral cortex by Immunohistochemistry.
  • ab121589, at 4 µg/ml, staining DLEC1 in PFA/Triton X-100 treated U 2 OS cells by immunofluorescence (green).

Anti-DLEC1 antibody (ab121589)参考文献

ab121589 has not yet been referenced specifically in any publications.

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