Anti-Dishevelled 3抗体(ab93850)
Key features and details
- Rabbit polyclonal to Dishevelled 3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Dishevelled 3抗体
参阅全部 Dishevelled 3 一抗 -
描述
兔多克隆抗体to Dishevelled 3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Recombinant Human Dishevelled 3 protein (ab114497) can be used as a positive control in WB. This antibody gave a positive signal in the following lysates: Ovary (Human) Tissue Lysate; Heart (Human) Tissue Lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab93850于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 mg/ml. Detects a band of approximately 78 kDa (predicted molecular weight: 78 kDa).
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说明 |
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WB
Use a concentration of 1 mg/ml. Detects a band of approximately 78 kDa (predicted molecular weight: 78 kDa). |
靶标
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功能
May play a role in the signal transduction pathway mediated by multiple Wnt genes. -
序列相似性
Belongs to the DSH family.
Contains 1 DEP domain.
Contains 1 DIX domain.
Contains 1 PDZ (DHR) domain. -
翻译后修饰
Ubiquitinated. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 1857 Human
- Entrez Gene: 13544 Mouse
- Entrez Gene: 303811 Rat
- Omim: 601368 Human
- SwissProt: Q92997 Human
- SwissProt: Q61062 Mouse
- Unigene: 388116 Human
- Unigene: 247259 Mouse
see all -
别名
- Dishevelled 3 (homologous to Drosophila dsh) antibody
- Dishevelled 3 antibody
- Dishevelled 3, dsh homolog (Drosophila) antibody
see all
图片
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All lanes : Anti-Dishevelled 3 antibody (ab93850) at 1 µg/ml
Lane 1 : Human ovary tissue lysate - total protein (ab30222)
Lane 2 : Human heart tissue lysate - total protein (ab29431)
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 78 kDa
Observed band size: 78 kDa
Additional bands at: 50 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 3 minutes
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab93850 被引用在 1 文献中.
- Gao M et al. Gandou decoction, a Chinese medicinal formula, in the treatment of hepatic injury by Wnt/ß-catenin pathway regulation in models of Wilson disease. Ann Palliat Med 9:2872-2885 (2020). PubMed: 32787367