概述

  • 产品名称
  • 描述
    兔多克隆抗体to DIRC2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 216-265 of Human DIRC2 (DIRC2

    AAESSRAHIKDRIEAVLYAEFGVVCLIFSATLAYFPPRPPLPPSVAAASQ

    )

  • 阳性对照
    • MCF7 Cell Lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab85188 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Electrogenic metabolite transporter.
  • 组织特异性
    Ubiquitous. Expressed in proximal tubular cells of the kidney.
  • 疾病相关
    Note=A chromosomal aberration involving DIRC2 has been found in a family with renal carcinoma. Translocation t(2;3)(q35;q21).
  • 序列相似性
    Belongs to the major facilitator superfamily.
  • 翻译后修饰
    Cleaved in lysosomes by cathepsin L between Leu-214 and Ala-261, generating a N-glycosylated N-terminal and a non-glycosylated C-terminal fragment.
  • 细胞定位
    Lysosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DIRC 2 antibody
    • dirc2 antibody
    • DIRC2_HUMAN antibody
    • Disrupted in renal cancer protein 2 antibody
    • Disrupted in renal carcinoma 2 antibody
    • Disrupted in renal carcinoma protein 2 antibody
    • FLJ14784 antibody
    • NP_116228 antibody
    • RCC 4 antibody
    • RCC4 antibody
    • Renal cell carcinoma 4 antibody
    see all

图片

  • Anti-DIRC2 antibody (ab85188) at 1 µg/ml + MCF7 Cell Lysate at 10 µg

    Predicted band size : 52 kDa

实验方案

文献

ab85188 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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