Full length human DIMT1L (NP_055288).
Rat brain tissue lysate and DIMT1L transfected 293T cell lysate.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 1X PBS, pH 7.2
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Protein G purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.
Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Nucleus > nucleolus.
Information by UniProt
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase antibody
18S rRNA dimethylase antibody
Anti-DIMT1L antibody (ab69434)参考文献
This product has been referenced in:
et al. The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis. Mol Biol Cell 26:2080-95 (2015).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"