Anti-Dihydrofolate reductase (DHFR)抗体,prediluted (ab82166)

概述

  • 产品名称
    Anti-Dihydrofolate reductase (DHFR)抗体,prediluted
    参阅全部 Dihydrofolate reductase (DHFR) 一抗
  • 描述
    兔多克隆抗体to Dihydrofolate reductase (DHFR),prediluted
  • 宿主
    Rabbit
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human Dihydrofolate reductase (DHFR) (internal sequence).

  • 阳性对照
    • Breast Carcinoma

性能

应用

Our Abpromise guarantee covers the use of ab82166 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Ready to use. Boil tissue section in 10mM Citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

靶标

  • 功能
    Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
  • 通路
    Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.
  • 序列相似性
    Belongs to the dihydrofolate reductase family.
    Contains 1 DHFR (dihydrofolate reductase) domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DHFR antibody
    • DHFRP1 antibody
    • Dihydrofolate reductase antibody
    • DYR antibody
    • DYR_HUMAN antibody
    • EC 1.5.1.3 antibody
    see all

图片

  • Formalin-fixed, paraffin-embedded section of Human breast carcinoma stained with Anti-DHFR antibody. Incubate primary antibody (ab82166) for 30 minutes at RT.

文献

ab82166 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your enquiry.

I have reviewed the immunogen sequences of the DHFR antibodies we have and regrettably the alignment with the e coli amino acid sequence is very low. Therefore, we would not anticipate that these antibodies would ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册