Anti-Dihydrofolate reductase (DHFR)抗体(ab54612)

概述

  • 产品名称Anti-Dihydrofolate reductase (DHFR)抗体
    参阅全部 Dihydrofolate reductase (DHFR) 一抗
  • 描述
    小鼠单克隆抗体to Dihydrofolate reductase (DHFR)
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: HFLSRSLDDA LKLTEQPELA NKVDMVWIVG GSSVYKEAMN HPGHLKLFVT RIMQDFESDT FFPEIDLEKY KLLPEYPGVL SDVQEEKGIK YKFEVYEKND , corresponding to amino acids 88-188 of Human Dihydrofolate reductase (DHFR)

性能

应用

Our Abpromise guarantee covers the use of ab54612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 21 kDa.
ICC/IF Use a concentration of 10 µg/ml.

靶标

  • 功能Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
  • 通路Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.
  • 序列相似性Belongs to the dihydrofolate reductase family.
    Contains 1 DHFR (dihydrofolate reductase) domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DHFR antibody
    • DHFRP1 antibody
    • Dihydrofolate reductase antibody
    • DYR antibody
    • DYR_HUMAN antibody
    • EC 1.5.1.3 antibody
    see all

Anti-Dihydrofolate reductase (DHFR) antibody 图像



  • Predicted band size : 21 kDa
  • ab54612 at 10 µg/ml staining Dihydrofolate reductase (DHFR) in human Hela cells by Immunocytochemistry / Immunofluorescence.

Anti-Dihydrofolate reductase (DHFR) antibody (ab54612)参考文献

This product has been referenced in:
  • Serova M  et al. Single agent and combination studies of pralatrexate and molecular correlates of sensitivity. Br J Cancer 104:272-80 (2011). WB ; Human . Read more (PubMed: 21179031) »

See 1 Publication for this product

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