概述
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产品名称Anti-DHX58抗体
参阅全部 DHX58 一抗 -
描述兔多克隆抗体to DHX58
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宿主Rabbit
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经测试应用适用于: WB, ELISA, IHC-Pmore details
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种属反应性与反应: Rat, Human
预测可用于: Mouse
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免疫原
Synthetic peptide corresponding to 11 internal sequence amino acids of Human DHX58 (NP_077024.2).
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阳性对照
- Rat kidney tissue lysate; Human Brain, Cortex tissue.
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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存储溶液Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度Protein A purified
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab115674 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 77 kDa. | |
| ELISA | Use at an assay dependent concentration. | |
| IHC-P | Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能Participates in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade which results in the induction and expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). The RNA helicase domain may recognize and structurally modify viral RNA to facilitate detection by DDX58/RIG-I or by IFIH1/MDA5 whose affinity for dsRNA is lower.
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序列相似性Belongs to the helicase family.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain. -
细胞定位Cytoplasm.
- Information by UniProt
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数据库链接
- Entrez Gene: 79132 Human
- Entrez Gene: 80861 Mouse
- Entrez Gene: 303538 Rat
- Omim: 608588 Human
- SwissProt: Q96C10 Human
- SwissProt: Q99J87 Mouse
- Unigene: 55918 Human
- Unigene: 271830 Mouse
see all -
别名
- D11LGP2 antibody
- D11lgp2e antibody
- DEXH (Asp Glu X His) box polypeptide 58 antibody
see all
图片
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Western blot - Anti-DHX58 antibody (ab115674)Lane 1 : Anti-DHX58 antibody (ab115674) at 1 µg/ml
Lane 2 : Anti-DHX58 antibody (ab115674) at 2 µg/ml
All lanes : Rat kidney tissue lysate
Predicted band size: 77 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DHX58 antibody (ab115674)ab115674, at 5µg/ml, staining DHX58 in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
文献
ab115674 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"