概述

  • 产品名称Anti-DGAT1抗体
    参阅全部 DGAT1 一抗
  • 描述
    兔多克隆抗体to DGAT1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Cow, Zebrafish
  • 免疫原

    A synthetic peptide designed within residues 200-300 of human DGAT1.

  • 阳性对照
    • HepG2 lysate.

相关产品

应用

Our Abpromise guarantee covers the use of ab54037 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa).
IHC-P Use at an assay dependent concentration. PubMed: 23499441

靶标

  • 功能Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly.
  • 通路Lipid metabolism; glycerolipid metabolism.
  • 序列相似性Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACAT related gene product 1 antibody
    • ACAT-related gene product 1 antibody
    • Acyl coenzyme A:cholesterol acyltransferase related gene 1 antibody
    • Acyl-CoA retinol O-fatty-acyltransferase antibody
    • Acyl-CoA:diacylglycerol acyltransferase antibody
    • ARAT antibody
    • ARGP1 antibody
    • C75990 antibody
    • D15Ertd23e antibody
    • Dgat antibody
    • DGAT1 antibody
    • DGAT1_HUMAN antibody
    • Diacylglycerol O acyltransferase 1 antibody
    • Diacylglycerol O-acyltransferase 1 antibody
    • DIAR7 antibody
    • Diglyceride acyltransferase antibody
    • EC 2.3.1.20 antibody
    • hCG_24006 antibody
    • MGC139064 antibody
    • Retinol O fatty acyltransferase antibody
    see all

Anti-DGAT1 antibody 图像

  • Anti-DGAT1 antibody (ab54037) at 2 µg/ml + HepG2 lysate

    Predicted band size : 55 kDa
    Observed band size : 55 kDa

Anti-DGAT1 antibody (ab54037)参考文献

This product has been referenced in:
  • Kirschmann EK  et al. Effects of Adolescent Cannabinoid Self-Administration in Rats on Addiction-Related Behaviors and Working Memory. Neuropsychopharmacology N/A:N/A (2016). Read more (PubMed: 27582345) »
  • Jin J  et al. Increased expression of enzymes of triglyceride synthesis is essential for the development of hepatic steatosis. Cell Rep 3:831-43 (2013). IHC-P . Read more (PubMed: 23499441) »

See all 3 Publications for this product

Product Wall

Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products.

I am sorry this product did not perform as stated on the datasheet and for the inconvenience this h...

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The sequence homology between human and Drosophila is only 42% and the immunogen sequence homology is also very less for cross reactivity. I am sorry to say this antibody might not be suitable for Drosophila specie...

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Thank you for your reply and the sequence.

Unfortunately, after investigation I confirm that none of the 4 anti-DGAT1 antibodies is likely to work in Drosophila. The immunogens used to raise ab59034, ab122924 and ab100982 do not show more than...

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Unfortunately, the source of the antibody informed us that Drosophila and human DGAT1 sequences are too divergent to recommend ab54037 for the detection of DGAT1 in fly.

We have 3 other references that may...

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Thank you for your e-mail and for attaching the scanned Western blot image.

My colleague is out of office for a couple of days this week and she has asked me to look after her customers during her absence.

The band appears to be at ...

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I would like to reassure you that this antibody is tested and covered by our 6 month guarantee forWBan...

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Thank you for taking the time to complete our questionnaire and contact us. I am sorry to hear you have had difficulty obtaining satisfactory results from this antibody. The details you have kindly provided will provide us with vital information for ou...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"