Anti-Desmoplakin抗体(ab106342)

概述

  • 产品名称Anti-Desmoplakin抗体
    参阅全部 Desmoplakin 一抗
  • 描述
    兔多克隆抗体to Desmoplakin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from an internal domain of Human Desmoplakin.

性能

应用

Our Abpromise guarantee covers the use of ab106342 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/5000. Predicted molecular weight: 331 kDa.

靶标

  • 相关性Desmosomes are the most common type of intercellular junction in vertebrate epithelial cells. They are characterized by 2 forms of interaction with other cellular structures. First, they form membrane anchorage sites for intermediate-size filaments, which are seen as electron-dense plaques evident beneath the plasma membrane. Second, a specific membrane core domain interacts with a corresponding domain of the plasma membrane of an adjacent cell, apparently mediating intercellular adhesion in a stable way. The desmosome intermediate filament complex is thought to impart tensile strength and resilience to the epithelium. Desmosomal proteins can be divided into 2 groups based on whether they fractionate with the urea-insoluble 'core' or the urea-soluble 'plaque' components. Desmoglein is, for example, a protein of the core. The main proteins of the plaque comprise the desmoplakins and plakoglobin.
  • 细胞定位Cell junction, desmosome. Cytoplasm, cytoskeleton.
  • 数据库链接
  • 别名
    • 250/210 kDa paraneoplastic pemphigus antigen antibody
    • Desmoplakin I antibody
    • Desmoplakin II antibody
    • DP I antibody
    • DP II antibody
    • DPI antibody
    • DPII antibody
    • DSP antibody
    • KPPS2 antibody
    • PPKS2 antibody
    see all

Anti-Desmoplakin antibody (ab106342)参考文献

ab106342 has not yet been referenced specifically in any publications.

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