Anti-Desmoglein 3抗体[MM0245- 4W25] (ab89177)

概述

  • 产品名称Anti-Desmoglein 3抗体[MM0245- 4W25]
    参阅全部 Desmoglein 3 一抗
  • 描述
    小鼠单克隆抗体[MM0245- 4W25] to Desmoglein 3
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length human Desmoglein 3 protein.

  • 常规说明This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized mouse).

性能

应用

Our Abpromise guarantee covers the use of ab89177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 108 kDa.
IHC-P 1/20 - 1/100.

靶标

  • 功能Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • 组织特异性Epidermis, tongue, tonsil, esophagus and carcinomas.
  • 序列相似性Contains 4 cadherin domains.
  • 结构域Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
  • 细胞定位Cell membrane. Cell junction > desmosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 130 kD pemphigus vulgaris antigen antibody
    • 130 kDa pemphigus vulgaris antigen antibody
    • Balding antibody
    • Cadherin family member 6 antibody
    • CDHF 6 antibody
    • CDHF6 antibody
    • Desmoglein 3 antibody
    • Desmoglein 3 precursor antibody
    • Desmoglein-3 antibody
    • Desmoglein3 antibody
    • DKFZp686P23184 antibody
    • DSG 3 antibody
    • DSG3 antibody
    • DSG3_HUMAN antibody
    • Pemphigus vulgaris antigen antibody
    • PVA antibody
    see all

Anti-Desmoglein 3 antibody [MM0245- 4W25] 图像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placental tissue section (4µm) labelling Desmoglein 3 with ab89177. Tissue was treated with 15µg/ml Protenase K for antigen retrieval and fixed with 4% PFA. A HRP-conjugated anti-mouse IgG was used as the secondary antibody (30 minutes at room temperature) followed by DAB color development.

Anti-Desmoglein 3 antibody [MM0245- 4W25] (ab89177)参考文献

ab89177 has not yet been referenced specifically in any publications.

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