Anti-Desmoglein 1抗体(ab123414)

概述

  • 产品名称
    Anti-Desmoglein 1抗体
    参阅全部 Desmoglein 1 一抗
  • 描述
    兔多克隆抗体to Desmoglein 1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 470-499 of Human Desmoglein 1 (NP_001933.2, Q02413).

  • 阳性对照
    • K562 cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab123414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 114 kDa.

靶标

  • 功能
    Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • 组织特异性
    Epidermis, tongue, tonsil and esophagus.
  • 疾病相关
    Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.
  • 序列相似性
    Contains 4 cadherin domains.
  • 结构域
    Calcium may be bound by the cadherin-like repeats.
  • 细胞定位
    Cell membrane. Cell junction > desmosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cadherin family member 4 antibody
    • CDHF4 antibody
    • Desmoglein-1 antibody
    • Desmosomal glycoprotein 1 antibody
    • DG1 antibody
    • DGI antibody
    • DSG antibody
    • DSG1 antibody
    • DSG1_HUMAN antibody
    • EPKHE antibody
    • EPKHIA antibody
    • Pemphigus foliaceus antigen antibody
    • PPKS1 antibody
    • SPPK1 antibody
    see all

图片

  • Anti-Desmoglein 1 antibody (ab123414) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 114 kDa

实验方案

文献

ab123414 has not yet been referenced specifically in any publications.

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