Anti-Dermatopontin抗体(ab118710)

概述

  • 产品名称Anti-Dermatopontin抗体
    参阅全部 Dermatopontin 一抗
  • 描述
    兔多克隆抗体to Dermatopontin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 45-94 (GFSYQCPHGQ VVVAVRSIFS KKEGSDRQWN YACMPTPQSL GEPTECWWEE) of Mouse Dermatopontin (NP_062733).

  • 阳性对照
    • Mouse pancreas lysate.

性能

应用

Our Abpromise guarantee covers the use of ab118710 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation.
  • 组织特异性Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.
  • 序列相似性Belongs to the dermatopontin family.
  • 翻译后修饰Sulfated on tyrosine residue(s).
  • 细胞定位Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DERM_HUMAN antibody
    • Dermatopontin antibody
    • Dpt antibody
    • TRAMP antibody
    • Tyrosine rich acidic matrix protein antibody
    • Tyrosine-rich acidic matrix protein antibody
    see all

Anti-Dermatopontin antibody 图像

  • Anti-Dermatopontin antibody (ab118710) at 1 µg/ml + Mouse pancreas lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG-HRP

    Predicted band size : 24 kDa

Anti-Dermatopontin antibody (ab118710)参考文献

ab118710 has not yet been referenced specifically in any publications.

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