概述

  • 产品名称Anti-DEPDC1抗体
    参阅全部 DEPDC1 一抗
  • 描述
    兔多克隆抗体to DEPDC1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide: PEPLLTFEYY ELFVNILVVC GYITVSDRSS GIHKIQDDPQ SSKFLHLNNL , corresponding to a region within internal sequence amino acids 287-336 of Human DEPDC1 (NP_001107592).

  • 阳性对照
    • Human fetal brain lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab107941 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 93 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
  • 组织特异性Expressed in testis. Up-regulated in bladder cancer cells (at protein level).
  • 序列相似性Contains 1 DEP domain.
    Contains 1 Rho-GAP domain.
  • 细胞定位Nucleus. Co-localizes with ZNF224 at the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 5830484J08Rik antibody
    • Cell cycle control protein SDP35 antibody
    • DEP domain containing 1 antibody
    • DEP domain containing protein 1A antibody
    • DEP domain-containing protein 1A antibody
    • DEP.8 antibody
    • DEP1A_HUMAN antibody
    • DEPDC 1 antibody
    • DEPDC 1A antibody
    • DEPDC1 antibody
    • DEPDC1-V2 antibody
    • Depdc1a antibody
    • FLJ20354 antibody
    • SDP 35 antibody
    • SDP35 antibody
    see all

Anti-DEPDC1 antibody 图像

  • Anti-DEPDC1 antibody (ab107941) at 1 µg/ml + Human Fetal Brain Lysate at 10 µg

    Predicted band size : 93 kDa

Anti-DEPDC1 antibody (ab107941)参考文献

ab107941 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"