概述

  • 产品名称
  • 描述
    山羊多克隆抗体to DENTT
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog
  • 免疫原

    Synthetic peptide corresponding to Human DENTT (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • 阳性对照
    • Human testis tissue.

性能

应用

Our Abpromise guarantee covers the use of ab122894 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能
    Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
  • 组织特异性
    Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.
  • 序列相似性
    Belongs to the nucleosome assembly protein (NAP) family.
  • 翻译后修饰
    Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.
  • 细胞定位
    Nucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CASK interacting nucleosome assembly protein antibody
    • CDA1 antibody
    • Cell division autoantigen 1 antibody
    • CINAP antibody
    • CTCL antibody
    • CTCL tumor antigen se20 4 antibody
    • CTCL-associated antigen se20-4 antibody
    • Cutaneous T cell lymphoma associated antigen se20 4 antibody
    • Cutaneous T cell lymphoma associated tumor antigen se20 4 antibody
    • Cutaneous T-cell lymphoma-associated antigen se20-4 antibody
    • Differentially Expressed Nucleolar TGF beta1 Target antibody
    • Differentially Expressed Nucleolar TGF beta1 Target protein antibody
    • Differentially-expressed nucleolar TGF-beta1 target protein antibody
    • HRIHFB2216 antibody
    • NP79 antibody
    • Nuclear protein of 79 kDa antibody
    • RP1 290F12.2 antibody
    • SE20 4 antibody
    • SE204 antibody
    • Testis specific protein Y encoded like 2 antibody
    • testis-specific protein Y encoded-like 2 antibody
    • Testis-specific Y-encoded-like protein 2 antibody
    • TSPX antibody
    • TSPY like 2 antibody
    • TSPY like protein 2 antibody
    • TSPY-like protein 2 antibody
    • TSPYL2 antibody
    • TSYL2_HUMAN antibody
    see all

图片

  • ab122894, at 5 µg/ml, staining CINAP in Formalin-fixed, Paraffin-embedded Human Testis tissue by Immunohistochemistry.

文献

ab122894 has not yet been referenced specifically in any publications.

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