The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 5 µg/ml.
功能Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
组织特异性Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.
序列相似性Belongs to the nucleosome assembly protein (NAP) family.
翻译后修饰Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.
细胞定位Nucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons.