Anti-Dengue Virus NS1 glycoprotein抗体[DN1] (ab41490)
Key features and details
- Mouse monoclonal [DN1] to Dengue Virus NS1 glycoprotein
- Suitable for: WB
- Reacts with: Dengue virus 2
- Isotype: IgG2a
概述
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产品名称
Anti-Dengue Virus NS1 glycoprotein抗体[DN1]
参阅全部 Dengue Virus NS1 glycoprotein 一抗 -
描述
小鼠单克隆抗体[DN1] to Dengue Virus NS1 glycoprotein -
宿主
Mouse -
特异性
Recognises the non-structural protein NS1 from Dengue Virus 2 (16681 strain). Reacts only weakly with NS1 from Dengue Virus 2 NGC strain, use ab41623 for detection of Dengue Virus 2 NGC NS1. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Dengue virus 2 -
免疫原
Full length native protein purified from Dengue Virus 2 infected supernatant
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.1% Proclin 150
Constituents: 10% BSA, 89.9% RPMI 1640 -
Concentration information loading...
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纯度
Tissue culture supernatant -
克隆
单克隆 -
克隆编号
DN1 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab41490于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/50 - 1/100. Use under non reducing condition. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
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说明 |
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WB
1/50 - 1/100. Use under non reducing condition. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa). |
靶标
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相关性
NS1 is one of 7 Dengue Virus non-structural proteins which are thought to be involved in viral replication. NS1 exists as a monomer in its immature form but is rapidly processed in the endoplasmic reticulum to form a stable dimer. A small amount of NS1 remains associated with intracellular organelles where it is thought to be involved in viral replication. The rest of NS1 is found either associated with the plasma membrane or secreted as a soluble hexadimer. NS1 is essential for viral viability but its precise biological function is unknown. Antibodies raised in response to NS1 in viral infection can cross react with cell surface antigens on epithelial cells and platelets and this has been implicated in the development of Dengue Hemorrhagic fever. -
数据库链接
- SwissProt: P29990 Dengue virus 2
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别名
- Dengue NS1 antibody
- Dengue Virus non structural protein 1 antibody
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab41490 被引用在 1 文献中.
- Callaway JB et al. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1ß Secretion: A Primary Human Monocyte Model. PLoS One 10:e0136708 (2015). PubMed: 26301593