概述

  • 产品名称Anti-Dematin抗体
    参阅全部 Dematin 一抗
  • 描述
    小鼠多克隆抗体to Dematin
  • 特异性Reactive against mammalian transfected lysate.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Full length Human Dematin protein (AAH52805.1).

  • 阳性对照
    • Rat brain cytoplasmic lysate Transfected 293T cytoplasmic lysate

性能

应用

Our Abpromise guarantee covers the use of ab89161 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa.

靶标

  • 功能Actin-bundling protein. May function in mitogen-activated protein kinase pathway.
  • 组织特异性Heart, brain, lung, skeletal muscle, and kidney.
  • 序列相似性Belongs to the villin/gelsolin family.
    Contains 1 HP (headpiece) domain.
  • 结构域Contains at least two actin-binding sites, one in the headpiece domain and one in the amino-terminal portion.
    Consists of a large core fragment, the amino-terminal portion, and a small headpiece, the C-terminal portion. The headpiece can bind but cannot bundle actin filaments.
  • 翻译后修饰Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase.
    The N-terminus is blocked.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DEMA antibody
    • DEMA_HUMAN antibody
    • Dematin antibody
    • DMT antibody
    • EPB49 antibody
    • erythrocyte membrane protein band 4.9 (dematin) antibody
    • Erythrocyte membrane protein band 4.9 antibody
    see all

Anti-Dematin antibody 图像

  • Anti-Dematin antibody (ab89161) at 1 µg/ml + Rat brain tissue lysate at 50 µg

    Predicted band size : 46 kDa
  • All lanes : Anti-Dematin antibody (ab89161) at 1 µg/ml

    Lane 1 : Dematin transfected 293T cell lysate
    Lane 2 : Non transfected cell 293T lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 46 kDa

Anti-Dematin antibody (ab89161)参考文献

This product has been referenced in:
  • Ryu MS  et al. Proteomic analysis shows the upregulation of erythrocyte dematin in zinc-restricted human subjects. Am J Clin Nutr 95:1096-102 (2012). Human . Read more (PubMed: 22456662) »

See 1 Publication for this product

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