概述

  • 产品名称Anti-delta Sarcoglycan抗体
    参阅全部 delta Sarcoglycan 一抗
  • 描述
    兔多克隆抗体to delta Sarcoglycan
  • 经测试应用适用于: WB, ICCmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from an internal region of Human delta Sarcoglycan.

性能

应用

Our Abpromise guarantee covers the use of ab92896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ICC
  • 应用说明ICC: 1/50 - 1/200.
    WB: 1/100 - 1/1000. Predicted molecular weight: 32 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
    • 组织特异性Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
    • 疾病相关Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder.
      Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
    • 序列相似性Belongs to the sarcoglycan beta/delta/gamma/zeta family.
    • 翻译后修饰Glycosylated.
      Disulfide bonds are present.
    • 细胞定位Cell membrane > sarcolemma. Cytoplasm > cytoskeleton.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 35 kDa dystrophin associated glycoprotein antibody
      • 35 kDa dystrophin-associated glycoprotein antibody
      • 35DAG antibody
      • CMD1L antibody
      • DAGD antibody
      • Delta-sarcoglycan antibody
      • Delta-SG antibody
      • Dystrophin associated glycoprotein delta sarcoglycan antibody
      • LGMD2F antibody
      • MGC22567 antibody
      • Placental delta sarcoglycan antibody
      • Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) antibody
      • SG delta antibody
      • SGCD antibody
      • SGCD_HUMAN antibody
      • SGCDP antibody
      • SGD antibody
      see all

    Anti-delta Sarcoglycan antibody (ab92896)参考文献

    This product has been referenced in:

    See 1 Publication for this product

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