Anti-delta Sarcoglycan抗体(ab113813)

概述

  • 产品名称Anti-delta Sarcoglycan抗体
    参阅全部 delta Sarcoglycan 一抗
  • 描述
    兔多克隆抗体to delta Sarcoglycan
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 37-86 (FVLLLMILIL VNLAMTIWIL KVMNFTIDGM GNLRITEKGL KLEGDSEFLQ) of Mouse delta Sarcoglycan (NP_036021).

  • 阳性对照
    • Mouse kidney cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab113813 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • 组织特异性Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
  • 疾病相关Defects in SGCD are the cause of limb-girdle muscular dystrophy type 2F (LGMD2F) [MIM:601287]. LGMD2F is an autosomal recessive disorder.
    Defects in SGCD are the cause of cardiomyopathy dilated type 1L (CMD1L) [MIM:606685]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
  • 序列相似性Belongs to the sarcoglycan beta/delta/gamma/zeta family.
  • 翻译后修饰Glycosylated.
    Disulfide bonds are present.
  • 细胞定位Cell membrane > sarcolemma. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 35 kDa dystrophin associated glycoprotein antibody
    • 35 kDa dystrophin-associated glycoprotein antibody
    • 35DAG antibody
    • CMD1L antibody
    • DAGD antibody
    • Delta-sarcoglycan antibody
    • Delta-SG antibody
    • Dystrophin associated glycoprotein delta sarcoglycan antibody
    • LGMD2F antibody
    • MGC22567 antibody
    • Placental delta sarcoglycan antibody
    • Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) antibody
    • SG delta antibody
    • SGCD antibody
    • SGCD_HUMAN antibody
    • SGCDP antibody
    • SGD antibody
    see all

Anti-delta Sarcoglycan antibody 图像

  • Anti-delta Sarcoglycan antibody (ab113813) at 1 µg/ml + Mouse kidney lysate at 10 µg

    Predicted band size : 32 kDa

Anti-delta Sarcoglycan antibody (ab113813)参考文献

ab113813 has not yet been referenced specifically in any publications.

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