Delta Opioid Receptor肽(ab38192)

概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 序列LVPSARAELQSSPLV
    • 氨基酸3 to 17

技术指标

Our Abpromise guarantee covers the use of ab38192 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • 补充说明Used for absorption control of antiserum binding.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

常规信息

  • 别名
    • D-OR-1
    • Delta type opioid receptor
    • Delta type opioid receptor DOR 1
    • Delta type opioid receptor DOR1
    • Delta-type opioid receptor
    • DOR 1
    • DOR-1
    • DOR1
    • mDOR
    • Nbor
    • Opioid receptor delta 1
    • OPRD
    • OPRD 1
    • OPRD_HUMAN
    • Oprd1
    see all
  • 相关性Function: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine. Tissue specificity: Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes. Similarity: Belongs to the G-protein coupled receptor 1 family. PTM: N-glycosylated. Ubiquitinated. A basal ubiquitination seems not to be related to degradation. Ubiquitination is increased upon formation of OPRM1:OPRD1 oligomers leading to proteasomal degradation; the ubiquitination is diminished by RTP4.
  • 细胞定位Multi pass membrane protein

Delta Opioid Receptor peptide (ab38192)参考文献

ab38192 has not yet been referenced specifically in any publications.

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