Anti-Delta Opioid Receptor抗体(ab10272)




Our Abpromise guarantee covers the use of ab10272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC 1/1000.
  • 应用说明Is unsuitable for IHC-Fr or IHC-P.
  • 靶标

    • 相关性Function: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine. Tissue specificity: Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes. Similarity: Belongs to the G-protein coupled receptor 1 family. PTM: N-glycosylated. Ubiquitinated. A basal ubiquitination seems not to be related to degradation. Ubiquitination is increased upon formation of OPRM1:OPRD1 oligomers leading to proteasomal degradation; the ubiquitination is diminished by RTP4.
    • 细胞定位Multi pass membrane protein
    • 数据库链接
    • 别名
      • D-OR-1 antibody
      • Delta type opioid receptor antibody
      • Delta type opioid receptor DOR 1 antibody
      • Delta type opioid receptor DOR1 antibody
      • Delta-type opioid receptor antibody
      • DOR 1 antibody
      • DOR-1 antibody
      • DOR1 antibody
      • mDOR antibody
      • Nbor antibody
      • Opioid receptor delta 1 antibody
      • OPRD 1 antibody
      • OPRD antibody
      • OPRD_HUMAN antibody
      • Oprd1 antibody
      see all

    Anti-Delta Opioid Receptor antibody 图像

    • ab10272 at 1/1000 dilution staining Delta Opioid Receptor in transfected cells by Immunocytochemistry.

    Anti-Delta Opioid Receptor antibody (ab10272)参考文献

    ab10272 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Immunocytochemistry
    Sample Human Cultured Cells (Human Neuroblastoma SHSY5Y)
    Specification Human Neuroblastoma SHSY5Y
    Fixative Paraformaldehyde
    Permeabilization No
    Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 25°C

    Mrs. Nada Charbaji

    Verified customer

    提交于 Sep 20 2010

    Thank you for your enquiry. Unfortunately, this product has not been tested in western blot application. However, by running a SwissProt analysis, the expected molecular weight is around 40kDa. I hope this information will be useful to you. Shoul...

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    Mark forwarded your request for a discount on ab10272 to my attention. We sell this product in units of 50µl and you have advised that you are likely to purchase 300-400 µl or 6-8 units. I would be pleased to offer you a 15% discount if you purchase 6-...

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    Thank you for your enquiry and your interest in our products. We would like to confirm that ab10272 has only been tested and characterised for ICC application, and we do not have any information if it works for Western. We are very sorry to infor...

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