Anti-delta 1 Catenin (phospho Y228)抗体[E205] (ab32403)


  • 产品名称Anti-delta 1 Catenin (phospho Y228)抗体[E205]
    参阅全部 delta 1 Catenin 一抗
  • 描述
    兔单克隆抗体[E205] to delta 1 Catenin (phospho Y228)
  • 特异性This antibody only detects delta 1 Catenin phosphorylated on Tyrosine 228.
  • 经测试应用适用于: WB, IHC-P, ICC, IPmore details
    不适用于: Flow Cyt
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A synthetic phospho peptide corresponding to residues surrounding Tyr 228 of human delta 1 Catenin.

  • 阳性对照
    • WB: HeLa cell lysate. IHC-P: Breast carcinoma.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.




Our Abpromise guarantee covers the use of ab32403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/5000 - 1/20000. Detects a band of approximately 115 kDa (predicted molecular weight: 108 kDa).
IHC-P 1/50.
ICC 1/100.
IP 1/100.
  • 应用说明Is unsuitable for Flow Cyt.
  • 靶标

    • 功能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
    • 组织特异性Expressed in vascular endothelium.
    • 序列相似性Belongs to the beta-catenin family.
      Contains 10 ARM repeats.
    • 结构域A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
    • 翻译后修饰Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
    • 细胞定位Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Cadherin associated Src substrate antibody
      • Cadherin-associated Src substrate antibody
      • CAS antibody
      • Catenin (cadherin associated protein) delta 1 antibody
      • Catenin delta 1 antibody
      • Catenin delta antibody
      • Catenin delta-1 antibody
      • CTND1_HUMAN antibody
      • CTNND 1 antibody
      • CTNND antibody
      • CTNND1 antibody
      • KIAA0384 antibody
      • p120 antibody
      • P120 CAS antibody
      • p120 catenin antibody
      • P120 CTN antibody
      • p120(cas) antibody
      • p120(ctn) antibody
      • P120CAS antibody
      • P120CTN antibody
      see all

    Anti-delta 1 Catenin (phospho Y228) antibody [E205] 图像

    • All lanes : Anti-delta 1 Catenin (phospho Y228) antibody [E205] (ab32403)

      Lane 1 : HeLa cell lysate, untreated.
      Lane 2 : HeLa cell lysate, treated with Pervanandate.
      Lane 3 : HeLa cell lysate, treated with Phosphatase.

      Predicted band size : 108 kDa
      Observed band size : 115 kDa (why is the actual band size different from the predicted?)
    • Ab32403, at a 1/50 dilution, staining delta 1 Catenin in paraffin embedded breast carcinoma tissue sections by Immunohistochemistry.

    Anti-delta 1 Catenin (phospho Y228) antibody [E205] (ab32403)参考文献

    This product has been referenced in:
    • Ma LW  et al. Phosphorylated p120-catenin expression has predictive value for oral cancer progression. J Clin Pathol 65:315-9 (2012). Read more (PubMed: 22259181) »

    See 1 Publication for this product

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