Anti-delta 1 Catenin (phospho T310)抗体[EPR2382] (ab81318)


  • 产品名称Anti-delta 1 Catenin (phospho T310)抗体[EPR2382]
    参阅全部 delta 1 Catenin 一抗
  • 描述
    兔单克隆抗体[EPR2382] to delta 1 Catenin (phospho T310)
  • 特异性The antibody only detects delta 1 Catenin when phosphorylated on Threonine 310.
  • 经测试应用适用于: WB, IHC-P, IPmore details
    不适用于: Flow Cyt or ICC/IF
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic phosphopeptide (Human)

  • 阳性对照
    • 293T cell lysates treated with calyculin A Human breast carcinoma tissue
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.



Our Abpromise guarantee covers the use of ab81318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 108 kDa.
IHC-P 1/100 - 1/250.
IP 1/10.
  • 应用说明Is unsuitable for Flow Cyt or ICC/IF.
  • 靶标

    • 功能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
    • 组织特异性Expressed in vascular endothelium.
    • 序列相似性Belongs to the beta-catenin family.
      Contains 10 ARM repeats.
    • 结构域A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
    • 翻译后修饰Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
    • 细胞定位Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Cadherin associated Src substrate antibody
      • Cadherin-associated Src substrate antibody
      • CAS antibody
      • Catenin (cadherin associated protein) delta 1 antibody
      • Catenin delta 1 antibody
      • Catenin delta antibody
      • Catenin delta-1 antibody
      • CTND1_HUMAN antibody
      • CTNND 1 antibody
      • CTNND antibody
      • CTNND1 antibody
      • KIAA0384 antibody
      • p120 antibody
      • P120 CAS antibody
      • p120 catenin antibody
      • P120 CTN antibody
      • p120(cas) antibody
      • p120(ctn) antibody
      • P120CAS antibody
      • P120CTN antibody
      see all

    Anti-delta 1 Catenin (phospho T310) antibody [EPR2382] 图像

    • All lanes : Anti-delta 1 Catenin (phospho T310) antibody [EPR2382] (ab81318) at 1/5000 dilution

      Lane 1 : 293T cell lysates untreated
      Lane 2 : 293T cell lysates treated with calyculin A

      Lysates/proteins at 10 µg per lane.

      HRP labelled goat anti rabbit at 1/2000 dilution

      Predicted band size : 108 kDa
      Observed band size : 108 kDa
      Additional bands at : 120 kDa. We are unsure as to the identity of these extra bands.
    • Immunohistochemical analysis of paraffin-embedded human breast carcinoma using ab81318 at 1/100 dilution.

    Anti-delta 1 Catenin (phospho T310) antibody [EPR2382] (ab81318)参考文献

    ab81318 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab81318.
    Please use the links above to contact us or submit feedback about this product.