Anti-delta 1 Catenin抗体(ab64479)

概述

  • 产品名称Anti-delta 1 Catenin抗体
    参阅全部 delta 1 Catenin 一抗
  • 描述
    兔多克隆抗体to delta 1 Catenin
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to C terminus of human delta 1 Catenin

  • 阳性对照
    • Human breast carcinoma tissue

性能

应用

Our Abpromise guarantee covers the use of ab64479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 for 30 min at room temperature.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
    • 组织特异性Expressed in vascular endothelium.
    • 序列相似性Belongs to the beta-catenin family.
      Contains 10 ARM repeats.
    • 结构域A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
    • 翻译后修饰Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
    • 细胞定位Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Cadherin associated Src substrate antibody
      • Cadherin-associated Src substrate antibody
      • CAS antibody
      • Catenin (cadherin associated protein) delta 1 antibody
      • Catenin delta 1 antibody
      • Catenin delta antibody
      • Catenin delta-1 antibody
      • CTND1_HUMAN antibody
      • CTNND 1 antibody
      • CTNND antibody
      • CTNND1 antibody
      • KIAA0384 antibody
      • p120 antibody
      • P120 CAS antibody
      • p120 catenin antibody
      • P120 CTN antibody
      • p120(cas) antibody
      • p120(ctn) antibody
      • P120CAS antibody
      • P120CTN antibody
      see all

    Anti-delta 1 Catenin antibody 图像

    • ab64479, at a dilution of 1/100, staining delta 1 Catenin in formalin fixed, paraffin embedded human breast carcinoma tissue by Immunohistochemistry.

    Anti-delta 1 Catenin antibody (ab64479)参考文献

    ab64479 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab64479.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"