Anti-delta 1 Catenin抗体[2234C6a] (ab50622)

概述

  • 产品名称Anti-delta 1 Catenin抗体[2234C6a]
    参阅全部 delta 1 Catenin 一抗
  • 描述
    小鼠单克隆抗体[2234C6a] to delta 1 Catenin
  • 经测试应用适用于: WB, ICC, Dot blotmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant human delta 1 Catenin fragment containing amino acids 50-200.

  • 阳性对照
    • recombinant human delta 1 catenin fragment.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab50622 was purified from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
  • 克隆单克隆
  • 克隆编号2234C6a
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab50622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ICC
Dot blot
  • 应用说明Dot: Use at an assay dependent dilution.
    ICC: 1/10.
    WB: 1/200. Detects a band of approximately 37 kDa (fragment); (predicted molecular weight: 108 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
    • 组织特异性Expressed in vascular endothelium.
    • 序列相似性Belongs to the beta-catenin family.
      Contains 10 ARM repeats.
    • 结构域A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
    • 翻译后修饰Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
    • 细胞定位Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Cadherin associated Src substrate antibody
      • Cadherin-associated Src substrate antibody
      • CAS antibody
      • Catenin (cadherin associated protein) delta 1 antibody
      • Catenin delta 1 antibody
      • Catenin delta antibody
      • Catenin delta-1 antibody
      • CTND1_HUMAN antibody
      • CTNND 1 antibody
      • CTNND antibody
      • CTNND1 antibody
      • KIAA0384 antibody
      • p120 antibody
      • P120 CAS antibody
      • p120 catenin antibody
      • P120 CTN antibody
      • p120(cas) antibody
      • p120(ctn) antibody
      • P120CAS antibody
      • P120CTN antibody
      see all

    Anti-delta 1 Catenin antibody [2234C6a] 图像

    Anti-delta 1 Catenin antibody [2234C6a] (ab50622)参考文献

    ab50622 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"