概述

  • 产品名称Anti-DECTIN 2抗体
    参阅全部 DECTIN 2 一抗
  • 描述
    兔多克隆抗体to DECTIN 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (FIVSCVVTYH FTYGETGKRL SELHSYHSSL TCFSEGTKVP AWGCCPASWK) of Human DECTIN 2 (NP_001007034).

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab99181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17 cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway.
  • 组织特异性Expressed in lung, spleen, lymph node, leukocytes, bone marrow, tonsils and dendritic cells. Strongly expressed in purified monocytes and weakly in B-cells. In peripheral blood cells, preferentially expressed in plasmacytoids rather than myeloids.
  • 序列相似性Contains 1 C-type lectin domain.
  • 结构域A short stretch of the intracellular domain (AA 8-14) proximal to the transmembrane domain is required for association with Fc receptor gamma chain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C type lectin domain family 6 member A antibody
    • C type lectin superfamily member 10 antibody
    • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10 antibody
    • C-type lectin domain family 6 member A antibody
    • C-type lectin superfamily member 10 antibody
    • CLC6A_HUMAN antibody
    • CLEC4N antibody
    • CLEC4N, mouse, homolog of antibody
    • Clec6a antibody
    • CLECSF10 antibody
    • DC associated C type lectin 2 antibody
    • DC-associated C-type lectin 2 antibody
    • Dectin-2 antibody
    • Dectin2 antibody
    • Dendritic cell associated lectin 2 antibody
    • Dendritic cell-associated C-type lectin 2 antibody
    see all

Anti-DECTIN 2 antibody (ab99181)参考文献

ab99181 has not yet been referenced specifically in any publications.

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