Anti-Decorin抗体(ab90425)

概述

  • 产品名称Anti-Decorin抗体
    参阅全部 Decorin 一抗
  • 描述
    山羊多克隆抗体to Decorin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cow, Pig, Macaque Monkey
  • 免疫原

    Synthetic peptide:

    KISRVDAASLKGLNN

    by a Cysteine residue linker, corresponding to internal sequence amino acids 232-246 of Human Decorin (NP_001911.1; NP_598011.1; NP_598012.1)

  • 阳性对照
    • Human Kidney lysate
  • 常规说明


    This antibody is expected to recognize the three reported isoforms a, b and c (NP_001911.1; NP_598011.1; NP_598012.1 resp.). Reported variants NP_598010.1 and NP_001911.1 represent identical protein.

性能

应用

Our Abpromise guarantee covers the use of ab90425 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 40 kDa).

靶标

  • 功能May affect the rate of fibrils formation.
  • 疾病相关Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
  • 序列相似性Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
    Contains 12 LRR (leucine-rich) repeats.
  • 翻译后修饰The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
  • 细胞定位Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Bone proteoglycan II antibody
    • CSCD antibody
    • DCN antibody
    • DCN protein antibody
    • Decorin antibody
    • Decorin proteoglycan antibody
    • Dermatan sulphate proteoglycans II antibody
    • DKFZp686J19238 antibody
    • DSPG 2 antibody
    • DSPG2 antibody
    • PG 40 antibody
    • PG II antibody
    • PG S2 antibody
    • PG-S2 antibody
    • PG40 antibody
    • PGII antibody
    • PGS 2 antibody
    • PGS2 antibody
    • PGS2_HUMAN antibody
    • Proteoglycan core protein antibody
    • SLRR1B antibody
    • Small leucine rich protein 1B antibody
    see all

Anti-Decorin antibody 图像

  • Anti-Decorin antibody (ab90425) at 0.5 µg/ml + Human kidney lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 40 kDa

Anti-Decorin antibody (ab90425)参考文献

ab90425 has not yet been referenced specifically in any publications.

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The immunogen of antibody ab90425 shows 66.6% homology than ab67449 which shows 83% with mouse sequence. Based on this data I presume ab90425 would be suitable.

Please note we do not have tested these anti...

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Thank you for your enquiry and your interest in our products. The immunogen sequence used to raise this antibody (ab90425) is published under the Immunogen: synthetic peptide: KISRVDAASLKGLNN by a Cysteine residue linker, corresponding to internal s...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"