概述

  • 产品名称
    Anti-Decorin抗体
    参阅全部 Decorin 一抗
  • 描述
    羊多克隆抗体to Decorin
  • 宿主
    Sheep
  • 特异性
    This antibody reacts with Decorin.
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Chicken, Cow, Human
    预测可用于: Mouse, Sheep, Rabbit, Horse, Dog, Xenopus laevis, Lizard, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    CVYVRSAIQLGNYK

    (Human) conjugated to KLH

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • 常规说明


    The C terminal human sequence used to raise this antibody is also Bone Proteoglycan II Precursor.

性能

应用

Our Abpromise guarantee covers the use of ab35378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/50 - 1/300.
WB Use at an assay dependent dilution. Predicted molecular weight: 40 kDa.

靶标

  • 功能
    May affect the rate of fibrils formation.
  • 疾病相关
    Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
  • 序列相似性
    Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
    Contains 12 LRR (leucine-rich) repeats.
  • 翻译后修饰
    The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
  • 细胞定位
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
    see all
  • 别名
    • Bone proteoglycan II antibody
    • CSCD antibody
    • DCN antibody
    • DCN protein antibody
    • Decorin antibody
    • Decorin proteoglycan antibody
    • Dermatan sulphate proteoglycans II antibody
    • DKFZp686J19238 antibody
    • DSPG 2 antibody
    • DSPG2 antibody
    • PG 40 antibody
    • PG II antibody
    • PG S2 antibody
    • PG-S2 antibody
    • PG40 antibody
    • PGII antibody
    • PGS 2 antibody
    • PGS2 antibody
    • PGS2_HUMAN antibody
    • Proteoglycan core protein antibody
    • SLRR1B antibody
    • Small leucine rich protein 1B antibody
    see all

实验方案

文献

This product has been referenced in:
  • Rao M  et al. Isobaric tags for relative and absolute quantification-based proteomic analysis of testis biopsies in rhesus monkeys treated with transient scrotal hyperthermia. Oncotarget 8:85909-85925 (2017). Read more (PubMed: 29156766) »
  • Yang G  et al. Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix. Biomaterials 34:9295-306 (2013). WB ; Cow . Read more (PubMed: 24044998) »

See all 2 Publications for this product

发表研究结果有使用 ab35378？请让我们知道，以便我们可以引用本数据表中的参考文章。

客户评价及客户问答

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1 Review or Q&A

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I am interested in an Abcam antibody for detection of mouse Decorin. Can this be conjugated to a radioisoptope?

Thank you for your interest in Abcam's antibodies, particularly anti-mouse decorin antibodies. None of our decorin antibodies have been tested for reactivity with murine decorin but at least one, ab35378, is predicted to react, based on homolog...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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