Anti-Decorin抗体(ab35378)

概述

• 产品名称
  Anti-Decorin抗体
  参阅全部 Decorin 一抗
• 描述
  羊多克隆抗体to Decorin
• 特异性
  This antibody reacts with Decorin.
• 经测试应用
  适用于: ELISA, WBmore details
• 种属反应性
  与反应: Chicken, Cow, Human
  预测可用于: Mouse, Sheep, Rabbit, Horse, Dog, Xenopus laevis, Lizard, Rhesus monkey
• 免疫原

  Synthetic peptide:

  CVYVRSAIQLGNYK

  (Human) conjugated to KLH

  Run BLAST with Run BLAST with
• 常规说明

  
  

  The C terminal human sequence used to raise this antibody is also Bone Proteoglycan II Precursor.

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• 存储溶液
  Preservative: 0.09% Sodium Azide
  Constituents: PBS, pH 7.2
• Concentration information loading...
• 纯度
  Protein G purified
• Primary antibody说明
  The C terminal human sequence used to raise this antibody is also Bone Proteoglycan II Precursor.
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Signal Transduction
  • Cytoskeleton / ECM
  • Extracellular Matrix
  • ECM Proteins
  • Collagen

  • Signal Transduction
  • Cytoskeleton / ECM
  • Extracellular Matrix
  • Structures
  • Bone

  • Stem Cells
  • Mesenchymal Stem Cells
  • Osteogenesis

应用

靶标

• 功能
  May affect the rate of fibrils formation.
• 疾病相关
  Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD) [MIM:610048]. Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance.
• 序列相似性
  Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
  Contains 12 LRR (leucine-rich) repeats.
• 翻译后修饰
  The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
• 细胞定位
  Secreted > extracellular space > extracellular matrix.

• Target information above from: UniProt accession P07585 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 280760 Cow
  • Entrez Gene: 1634 Human
  • Entrez Gene: 13179 Mouse
  • Entrez Gene: 100009171 Rabbit
  • Entrez Gene: 443048 Sheep
  • Omim: 125255 Human
  • SwissProt: P21793 Cow
  • SwissProt: P07585 Human

  • SwissProt: P28654 Mouse
  • SwissProt: Q28888 Rabbit
  • SwissProt: Q9TTE2 Sheep
  • Unigene: 728830 Human
  • Unigene: 56769 Mouse

  see all
• 别名
  • Bone proteoglycan II antibody
  • CSCD antibody
  • DCN antibody

  • DCN protein antibody
  • Decorin antibody
  • Decorin proteoglycan antibody
  • Dermatan sulphate proteoglycans II antibody
  • DKFZp686J19238 antibody
  • DSPG 2 antibody
  • DSPG2 antibody
  • PG 40 antibody
  • PG II antibody
  • PG S2 antibody
  • PG-S2 antibody
  • PG40 antibody
  • PGII antibody
  • PGS 2 antibody
  • PGS2 antibody
  • PGS2_HUMAN antibody
  • Proteoglycan core protein antibody
  • SLRR1B antibody
  • Small leucine rich protein 1B antibody

  see all

实验方案

• Western blot protocols