Anti-DDX4 / MVH抗体(ab119322)

概述

  • 产品名称Anti-DDX4 / MVH抗体
    参阅全部 DDX4 / MVH 一抗
  • 描述
    兔多克隆抗体to DDX4 / MVH
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide from around the site corresponding to amino acids 273-277 (

    TILVE

    ) of Human DDX4/ MVH, conjugated to KLH

  • 阳性对照
    • HeLa, K562 and 3T3 cell lysates.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab119322 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 79 kDa.

靶标

  • 功能Probable ATP-dependent RNA helicase required during spermatogenesis (PubMed:10920202, PubMed:21034600). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle.
  • 组织特异性Expressed only in ovary and testis. Expressed in migratory primordial germ cells in the region of the gonadal ridge in both sexes.
  • 序列相似性Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • 细胞定位Cytoplasm. Cytoplasm, perinuclear region. Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DDX 4 antibody
    • Ddx4 antibody
    • DDX4_HUMAN antibody
    • DEAD (Asp Glu Ala Asp) box polypeptide 4 antibody
    • DEAD box protein 4 antibody
    • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4 antibody
    • MVH antibody
    • Probable ATP dependent RNA helicase DDX4 antibody
    • Probable ATP-dependent RNA helicase DDX4 antibody
    • VASA antibody
    • Vasa homolog antibody
    see all

Anti-DDX4 / MVH antibody 图像

  • All lanes : Anti-DDX4 / MVH antibody (ab119322) at 1/500 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : K562 cell lysate
    Lane 3 : 3T3 cell lysate


    Predicted band size : 79 kDa

Anti-DDX4 / MVH antibody (ab119322)参考文献

ab119322 has not yet been referenced specifically in any publications.

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