概述

  • 产品名称Anti-DDX26抗体
    参阅全部 DDX26 一抗
  • 描述
    兔多克隆抗体to DDX26
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rabbit, Horse, Cow, Pig, Chimpanzee, Rhesus monkey, Gorilla, Opossum, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residue 750 and 800 of Human DDX26 (NP_036273.1).

  • 阳性对照
    • Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Prostate Carcinoma.
  • 常规说明The concentration of IgG is less than or equal to 1 mg/ml.

性能

应用

Our Abpromise guarantee covers the use of ab114075 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Antigen retrieval is recommended. Likely to work with frozen sections In some cases, the antibody may be diluted further than indicated.

靶标

  • 功能Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.
  • 组织特异性Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 序列相似性Belongs to the Integrator subunit 6 family.
    Contains 1 VWFA domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DBI 1 antibody
    • DBI-1 antibody
    • DBI1 antibody
    • DDX26 antibody
    • DDX26A antibody
    • DEAD box protein antibody
    • DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26 antibody
    • Deleted in cancer 1 antibody
    • DICE1 antibody
    • DKFZp434B105 antibody
    • HDB antibody
    • Int6 antibody
    • INT6_HUMAN antibody
    • Integrator complex subunit 6 antibody
    • INTS 6 antibody
    • ints6 antibody
    • Notchl2 antibody
    • OTTHUMP00000018439 antibody
    • OTTHUMP00000215034 antibody
    • OTTHUMP00000215036 antibody
    • Protein DDX26 antibody
    • Protein deleted in cancer 1 antibody
    • RNA helicase HDB antibody
    see all

Anti-DDX26 antibody 图像

  • ab114075 at 1/250 dilution staining DDX26 in Formalin-Fixed, Paraffin-Embedded prostate carcinoma tissue by Immunohistochemistry. Detection utilised DAB.

Anti-DDX26 antibody (ab114075)参考文献

ab114075 has not yet been referenced specifically in any publications.

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