概述

  • 产品名称Anti-DDX21抗体
    参阅全部 DDX21 一抗
  • 描述
    兔多克隆抗体to DDX21
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Horse, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residues 725 and the C-terminal (residue 783) of Human DDX21 (NP_004719.2)

  • 阳性对照
    • Human larynx squamous cell carcinoma. Mouse squamous cell carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab84394 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Can unwind double-stranded RNA (helicase) and can fold or introduce a secondary structure to a single-stranded RNA (foldase). Functions as cofactor for JUN-activated transcription. Involved in rRNA processing.
  • 序列相似性Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • 结构域The two enzymatic activities reside in two separate domains, the helicase in the N-terminus and the foldase in the C-terminus.
    The 3 X 5 AA repeats seem to be critical for the RNA folding activity.
  • 细胞定位Nucleus > nucleolus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Ddx21 antibody
    • DDX21_HUMAN antibody
    • DEAD (Asp-Glu-Ala-Asp) box helicase 21 antibody
    • DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 antibody
    • DEAD box protein 21 antibody
    • EC 3.6.1.- antibody
    • Gu alpha antibody
    • Gu protein antibody
    • Gu-alpha antibody
    • GUA antibody
    • GURDB antibody
    • Nucleolar RNA helicase 2 antibody
    • Nucleolar RNA helicase Gu antibody
    • Nucleolar RNA helicase II antibody
    • RH II/Gu antibody
    • RH II/GuA antibody
    • RNA helicase II/Gu alpha antibody
    see all

Anti-DDX21 antibody 图像

  • Detection of Human DDX21 by Immunohistochemistry.
    Sample: FFPE section of Human larynx squamous cell carcinoma.
    Antibody: ab84394 used at a dilution of 1/250.
    Detection: DAB.
  • Detection of Mouse DDX21 by Immunohistochemistry.
    Sample: FFPE section of Mouse squamous cell carcinoma.
    Antibody: ab84394 used at a dilution of 1/250.
    Detection: DAB.

Anti-DDX21 antibody (ab84394)参考文献

This product has been referenced in:
  • Lund RR  et al. NADH-Cytochrome b5 Reductase 3 Promotes Colonization and Metastasis Formation and Is a Prognostic Marker of Disease-Free and Overall Survival in Estrogen Receptor-Negative Breast Cancer. Mol Cell Proteomics 14:2988-99 (2015). IHC-P ; Human . Read more (PubMed: 26351264) »

See 1 Publication for this product

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