概述

  • 产品名称Anti-DCXR抗体
    参阅全部 DCXR 一抗
  • 描述
    兔多克隆抗体to DCXR
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cynomolgus Monkey
  • 免疫原

    VMTSMGQATW SDPHKAKTML NRIPLGKFAE VEHVVNAILF LLSDRSGMTT GSTLPVEGGF WAC, corresponding to amino acids 182-244 of Human DCXR (NP_057370).

  • 阳性对照
    • HepG2 whole cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab96778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 26 kDa.

靶标

  • 功能Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • 组织特异性Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • 疾病相关Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.
  • 序列相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 细胞定位Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Carbonyl reductase 2 antibody
    • Carbonyl reductase II antibody
    • DCR antibody
    • Dcxr antibody
    • DCXR_HUMAN antibody
    • Dicarbonyl L xylulose reductase antibody
    • Dicarbonyl/ L xylulose reductase antibody
    • Dicarbonyl/L-xylulose reductase antibody
    • HCR2 antibody
    • HCRII antibody
    • Human carbonyl reductase 2 antibody
    • kiDCR antibody
    • Kidney dicarbonyl reductase antibody
    • L xylulose reductase antibody
    • L-xylulose reductase antibody
    • P34H antibody
    • PNTSU antibody
    • SDR20C1 antibody
    • Short chain dehydrogenase/reductase family 20C member 1 antibody
    • Sperm surface protein P34H antibody
    • XR antibody
    see all

Anti-DCXR antibody 图像

  • Anti-DCXR antibody (ab96778) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 26 kDa

Anti-DCXR antibody (ab96778)参考文献

ab96778 has not yet been referenced specifically in any publications.

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